The n all countries it is forbidden any kind of trade in eggs, sperm and gametes. With the donation, the giver makes a voluntary act, which takes place in the same way with the donation of blood. According to Law 40 of 2004 in Italy are forbidden techniques of heterologous fertilization . The donation is then carried out in our international centers where this practice is permitted. In Spain, for example, the female gamete donation is regulated by Law 35/1988. Egg donation, according to this rule, it is a gesture entirely altruistic and voluntary. Giver does it anonymously and provides her ova to the Donation Program and not to a specific patient.